Fig. 1 · Structure

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S-0636

Glutamyl Cyclase Inhibitor

S-0636 is a selective inhibitor of glutamyl cyclase (QC), demonstrating low cytotoxicity and resistance profiles. This compound effectively targets and inhibits virulence factors of Porphyromonas gingivalis, making it a valuable tool for investigating bacterial infections. Its specificity and efficacy support its application in studies aimed at understanding the role of QC in pathogenicity and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2374924-42-0
Applications Glutamyl Cyclase Inhibitor
Formula C16H19N7O
Molecular Weight 325.37
SMILES
N=C(NCCOC1=CC=C(C=C1)CNC2=CN=C3N=CNC3=C2)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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