(S)-10-Hydroxycamptothecin-d5

Catalog No.: A32962
Stable Isotope
(S)-10-Hydroxycamptothecin-d5 is a stable isotope-labeled form of (S)-10-Hydroxycamptothecin, a potent inhibitor of DNA topoisomerase I. This compound exhibits significant apoptosis-inducing properties, making it valuable in the study of cancer biology. Its applications extend to research involving hepatoma, gastric carcinoma, colon cancer, and leukemia, enabling detailed investigations into the mechanisms of action and therapeutic potential of topoisomerase I inhibition.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S)-10-Hydroxycamptothecin-d5 is a stable isotope-labeled form of (S)-10-Hydroxycamptothecin, a potent inhibitor of DNA topoisomerase I. This compound exhibits significant apoptosis-inducing properties, making it valuable in the study of cancer biology. Its applications extend to research involving hepatoma, gastric carcinoma, colon cancer, and leukemia, enabling detailed investigations into the mechanisms of action and therapeutic potential of topoisomerase I inhibition.
Product Information
Catalog NumA32962
FormulaC20H11D5N2O5
Molecular Weight369.38
CAS Number1330277-66-1
SMILESO=C1N2C(C=3C(C2)=CC=4C(N3)=CC=C(O)C4)=CC5=C1COC(=O)[C@@]5(C(C([2H])([2H])[2H])([2H])[2H])O
Synonyms10-HCPT-d5; 10-Hydroxycamptothecin-d5
Useful Calculator

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