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(S)-10-Hydroxycamptothecin-d5

Stable Isotope

(S)-10-Hydroxycamptothecin-d5 is a stable isotope-labeled form of (S)-10-Hydroxycamptothecin, a potent inhibitor of DNA topoisomerase I. This compound exhibits significant apoptosis-inducing properties, making it valuable in the study of cancer biology. Its applications extend to research involving hepatoma, gastric carcinoma, colon cancer, and leukemia, enabling detailed investigations into the mechanisms of action and therapeutic potential of topoisomerase I inhibition.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1330277-66-1
Applications	Stable Isotope
Formula	C₂₀H₁₁D₅N₂O₅
Molecular Weight	369.38
Synonyms	10-HCPT-d5; 10-Hydroxycamptothecin-d5
SMILES	O=C1N2C(C=3C(C2)=CC=4C(N3)=CC=C(O)C4)=CC5=C1COC(=O)[C@@]5(C(C([2H])([2H])[2H])([2H])[2H])O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.