Fig. 1 · Structure

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S-3483

Glc-6-Pase Inhibitor

S-3483 is a potent inhibitor of glucose-6-phosphatase (Glc-6-Pase), functioning through a reversible, linear competitive mechanism. With a Ki value of 129 nM in rat liver microsomes, S-3483 effectively targets the Glc-6-P transporter specifically in renal and liver microsomes. This compound is essential for research in metabolic regulation and offers potential applications in diabetes and related metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 160341-09-3
Applications Glc-6-Pase Inhibitor
Formula C26H27ClO8
Molecular Weight 502.94
SMILES
O=C([C@]1(OC[C@H]2[C@@H](C3=CC=C(Cl)C=C3)C2)C[C@@H](O)[C@@H](O)[C@H](OC(/C=C/C4=CC=C(O)C=C4)=O)C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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