Fig. 1 · Structure
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(S)-4-Hydroxymephenytoin
Mephenytoin metabolite
(S)-4-Hydroxymephenytoin is a metabolite formed through the stereoselective metabolism of mephenytoin, primarily interacting with cytochrome P450 enzymes CYP2C19 and CYP2B6. This compound plays a crucial role in the pharmacokinetics of mephenytoin, an anticonvulsant drug, by influencing its metabolic pathway. It is utilized in research to study drug interactions, metabolic profiling, and the effects of polymorphisms in metabolic enzymes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 82695-93-0 |
| Applications | Mephenytoin metabolite |
| Formula | C12H14N2O3 |
| Molecular Weight | 234.25 |
| SMILES | CC[C@]1(C2=CC=C(C=C2)O)C(N(C(N1)=O)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.