Fig. 1 · Structure
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(S)-4C3HPG
mGluR 1a Antagonist/GluR2 Agonist
(S)-4C3HPG, a selective antagonist of metabotropic glutamate receptor 1a (mGluR 1a) and agonist of GluR2, exhibits significant anticonvulsant properties. This compound demonstrates protective effects against audiogenic seizures in DBA/2 mice, making it a valuable tool for research in epilepsy and related neurological disorders. Its dual action on glutamate receptors positions (S)-4C3HPG as a promising candidate for studies aimed at understanding the modulation of excitatory neurotransmission.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 85148-82-9 |
| Applications | mGluR 1a Antagonist/GluR2 Agonist |
| Formula | C9H9NO5 |
| Molecular Weight | 211.17 |
| Synonyms | (S)-4-Carboxy-3-hydroxyphenylglycine |
| SMILES | OC1=C(C(O)=O)C=CC([C@H](N)C(O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.