Fig. 1 · Structure
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(S)-Bleximenib
Bleximenib Isoform
(S)-Bleximenib is an isoform of Bleximenib that primarily targets MEIS1 mRNA expression. It displays an IC50 value greater than 1 μM in related assays, indicating its potential utility in modulating gene expression. This compound is valuable for research into acute myeloid leukemia, contributing to the understanding of its molecular mechanisms and therapeutic approaches.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2654081-27-1 |
| Applications | Bleximenib Isoform |
| Formula | C32H50FN7O3 |
| Molecular Weight | 599.78 |
| Synonyms | (S)-JNJ-75276617; (S)-Menin-MLL inhibitor 24 |
| SMILES | COCCN(C)CCC[C@H](N1CC2(C1)CN(C3=NC=NN=C3OC4=C(C=C(C=C4)F)C(N(CC)C(C)C)=O)CC2)C(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.