Fig. 1 · Structure
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(S)-CE-123
Dopamine Transporter Inhibitor
(S)-CE-123 is a potent and selective inhibitor of the dopamine transporter (DAT), demonstrating an EC50 of 2.76 μM in uptake inhibition assays with HEK293 cells expressing human DAT isoforms. As a Modafinil analogue, it effectively crosses the blood-brain barrier. Research indicates that (S)-CE-123 enhances cognitive and motivational processes in preclinical models, making it a valuable tool for studies related to dopamine modulation and neuropharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2378384-49-5 |
| Applications | Dopamine Transporter Inhibitor |
| Formula | C17H15NOS2 |
| Molecular Weight | 313.44 |
| SMILES | O=[S@@](CC1=CN=CS1)C(C2=CC=CC=C2)C3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.