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S-Petasin

Phosphodiesterase Inhibitor

S-Petasin is a phosphodiesterase (PDE) inhibitor targeting both PDE3 and PDE4 with IC50 values of 25.5 μM and 17.5 μM, respectively. This compound exhibits significant biological activities, including the induction of apoptosis and modulation of inflammatory responses, making it valuable for studying conditions such as prostate cancer, obesity, melanoma, and allergic asthma. Additionally, S-Petasin influences multiple signaling pathways and cellular processes, including caspase activation and regulation of apoptosis-related proteins. Its ability to reduce inflammatory cell accumulation and cytokine levels adds to its potential as an anti-inflammatory agent in research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	70238-51-6
Applications	Phosphodiesterase Inhibitor
Formula	C₁₉H₂₆O₃S
Molecular Weight	334.47
SMILES	C[C@@H]([C@@H](CCC1=CC2=O)OC(/C=C\SC)=O)[C@@]1(C)C[C@H]2C(C)=C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.