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(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA

Catalog No.: A80036
E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is an E3 ligase ligand-linker conjugate designed for use in PROTAC (Proteolysis Targeting Chimeras) applications. This compound features the (S,R,S)-AHPC ligand along with a three-unit PEG linker, facilitating targeted protein degradation through the ubiquitin-proteasome system. It is suitable for studies involving E3 ligase modulation and the development of novel therapeutic strategies.
(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA 2417370-48-8 E3 Ligase Ligand-Linker Conjugate
Grouped product items
Size Price Stock Qty
5mg
$245.00
In stock
10mg
$405.00
In stock
25mg
$800.00
In stock
50mg
$1,190.00
In stock
100mg
$1,800.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is an E3 ligase ligand-linker conjugate designed for use in PROTAC (Proteolysis Targeting Chimeras) applications. This compound features the (S,R,S)-AHPC ligand along with a three-unit PEG linker, facilitating targeted protein degradation through the ubiquitin-proteasome system. It is suitable for studies involving E3 ligase modulation and the development of novel therapeutic strategies.
Product Information
Catalog NumA80036
FormulaC38H56F3N5O13S3
Molecular Weight944.07
CAS Number2417370-48-8
SMILESO=C(N(C[C@@H]1OC(OC(C)C(C)S[S](C)(=O)=O)=O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCCOCCN)=O.OC(C(F)(F)F)=O
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PROTAC > E3 Ligase Ligand-Linker Conjugate