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(S,R,S)-AHPC-Ac

Ligand for E3 Ligase

(S,R,S)-AHPC-Ac is a ligand for E3 ubiquitin ligases, facilitating the ubiquitination process crucial for protein degradation. This compound is instrumental in the development of PROTACs, such as SMARCA2/4-degrader-22, and is utilized in research focusing on targeted protein degradation mechanisms. Its role in modulating E3 ligase activity makes it valuable for studies in cellular signaling and protein homeostasis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2361116-63-2
Applications	Ligand for E3 Ligase
Formula	C₂₄H₃₂N₄O₄S
Molecular Weight	472.60
SMILES	CC(C)(C)[C@H](N)C(N1[C@@H](C[C@H](C1)OC(C)=O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.