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(S,R,S)-AHPC-amide-C10-azide

Ligand for E3 Ligase

(S,R,S)-AHPC-amide-C10-azide is a potent ligand for the E3 ubiquitin ligase VHL, facilitating the recruitment of the VHL protein. This compound can be conjugated to target protein ligands through a linker, enabling the development of PROTACs for targeted protein degradation studies. Its unique structure and functionality make it a valuable tool for researchers investigating ubiquitin-proteasome pathways and exploring novel therapeutics in cancer and other diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2906183-85-3
Applications	Ligand for E3 Ligase
Formula	C₃₃H₄₉N₇O₄S
Molecular Weight	639.86
SMILES	C([C@@H](NC(CCCCCCCCCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.