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(S,R,S)-AHPC-O-CF3

Ligand for E3 Ligase

(S,R,S)-AHPC-O-CF3 serves as a ligand for E3 ubiquitin ligases, facilitating targeted protein degradation through the ubiquitin-proteasome system. This compound can be utilized in the synthesis of PROTAC SMARCA2/4-degrader-20, which is instrumental for studying the modulation of SMARCA2 and SMARCA4 proteins. Its applications extend to research involving targeted therapy and novel drug development strategies in cancer and other diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2641373-92-2
Applications	Ligand for E3 Ligase
Formula	C₂₃H₂₉F₃N₄O₄S
Molecular Weight	514.56
SMILES	CC(C)(C)[C@H](N)C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(C=C(C3=C(N=CS3)C)C=C2)OC(F)(F)F)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.