Fig. 1 · Structure

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(S,R,S)-AHPC-PEG5-Azide

Ligand for E3 Ligase

(S,R,S)-AHPC-PEG5-Azide is a VHL ligand that specifically targets the von Hippel-Lindau (VHL) protein. This compound serves as a pivotal component for the formation of PROTACs (proteolysis-targeting chimeras) by facilitating the recruitment of E3 ligases to target proteins. Its utility in targeted protein degradation research makes it invaluable for studies focused on regulating protein levels and functions in cellular environments.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3036242-05-1
Applications Ligand for E3 Ligase
Formula C34H51N7O9S
Molecular Weight 733.88
SMILES
[N-]=[N+]=NCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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