Fig. 1 · Structure
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(S)-Roscovitine
CDKs Inhibitor
(S)-Roscovitine is a selective inhibitor of cyclin-dependent kinases (CDKs), demonstrating the ability to cross the blood-brain barrier effectively. This compound exhibits neuroprotective properties, making it a valuable tool in the study of neurodegenerative conditions and stroke research. Its ability to modulate CDK activity is pivotal for investigating cell cycle regulation and potential therapeutic strategies in neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 186692-45-5 |
| Applications | CDKs Inhibitor |
| Formula | C19H26N6O |
| Molecular Weight | 354.45 |
| Synonyms | (S)-Seliciclib; (S)-CYC202 |
| SMILES | CC[C@H](NC1=NC(NCC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.