Fig. 1 · Structure
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(S,S)-BMS-984923
(S,S)-Enantiomer of BMS-984923
(S,S)-BMS-984923 is the less active (S,S)-enantiomer of the potent mGluR5 silent allosteric modulator, BMS-984923, exhibiting an EC50 greater than 1 μM for the mGluR5 receptor. This compound serves as a valuable tool in research focusing on modulation of metabotropic glutamate receptors. Additionally, (S,S)-BMS-984923 features an alkyne functional group, enabling the compound to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, making it suitable for applications in click chemistry.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1375752-77-4 |
| Applications | (S,S)-Enantiomer of BMS-984923 |
| Formula | C22H15ClN2O2 |
| Molecular Weight | 374.82 |
| SMILES | ClC1=C(C=CC=C1)[C@@]2([H])[C@@](C3=CN=CC(C#CC4=CC=CC=C4)=C3)([H])NC(O2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.