Fig. 1 · Structure
Documents & Downloads
(S,S)-GSK321
Cat. No.
A75795
CAS
1816272-20-4
IDH Inhibitor
(S,S)-GSK321 is a selective inhibitor of isocitrate dehydrogenase (IDH), specifically targeting mutated forms of the enzyme. This compound exhibits significant anti-cancer activity by disrupting the metabolic pathways in cells with IDH mutations. It is primarily utilized in research focused on cancer therapeutics and metabolic disease modeling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1816272-20-4 |
| Applications | IDH Inhibitor |
| Formula | C28H28FN5O3 |
| Molecular Weight | 501.55 |
| SMILES | C[C@H](O)C1=CC=CC(NC(C2=NN(C3=C2CN(C[C@@H]3C)C(C4=CC=CN4)=O)CC5=CC=C(C=C5)F)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.