Fig. 1 · Structure
Documents & Downloads
(S,S,R,S,R)-Boc-Dap-NE
MMAE Intermediate
(S,S,R,S,R)-Boc-Dap-NE is a key intermediate in the synthesis of Monomethyl auristatin E (MMAE), a potent inhibitor of tubulin polymerization. This dipeptide derivative is crucial for the development of Antibody-Drug Conjugates (ADCs) that utilize MMAE as a cytotoxic component. Researchers can leverage this compound for applications in targeted cancer therapies and studies of microtubule dynamics.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3026595-14-9 |
| Applications | MMAE Intermediate |
| Formula | C23H36N2O5 |
| Molecular Weight | 420.54 |
| SMILES | O=C(N1[C@@H](CCC1)[C@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)OC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.