Fig. 1 · Structure
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(S,S,S)-AHPC-Boc
Isomer
(S,S,S)-AHPC-Boc is a stereoisomer of (S,R,S)-AHPC-Boc and serves as a valuable experimental control in research. This compound specifically relates to the recruitment of the von Hippel-Lindau (VHL) protein, which plays a critical role in targeted protein degradation through PROTAC technology. By providing a reliable reference point, (S,S,S)-AHPC-Boc facilitates investigations into the efficacy and selectivity of VHL ligands in cellular systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 1797406-74-6 |
| Applications | Isomer |
| Formula | C27H38N4O5S |
| Molecular Weight | 530.68 |
| Synonyms | (S,S,S)-VH032-Boc |
| SMILES | O=C(N1C[C@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.