(S,S,S)-VH032-cyclopropane-F is a ligand that targets E3 ubiquitin ligases, facilitating the selective degradation of specific proteins through the ubiquitin-proteasome system. This compound can be conjugated to target protein ligands using a linker to generate PROTAC derivatives, such as cis-VZ185, which are valuable tools for studying protein dynamics and cellular functions. Its unique mechanism provides opportunities for innovative research in targeted protein degradation and therapeutic development.
(S,S,S)-VH032-cyclopropane-F is a ligand that targets E3 ubiquitin ligases, facilitating the selective degradation of specific proteins through the ubiquitin-proteasome system. This compound can be conjugated to target protein ligands using a linker to generate PROTAC derivatives, such as cis-VZ185, which are valuable tools for studying protein dynamics and cellular functions. Its unique mechanism provides opportunities for innovative research in targeted protein degradation and therapeutic development.
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