Fig. 1 · Structure

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(S,S)-Sinogliatin

Enantiomer

(S,S)-Sinogliatin is the (S,S)-enantiomer of the glucokinase activator Sinogliatin, specifically targeting glucokinase to enhance its activity. This compound demonstrates significant potential in the modulation of glucose metabolism, making it a valuable tool for research applications related to type 2 diabetes. Its use can aid in investigating the therapeutic mechanisms underlying glucose homeostasis and pancreatic function.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 1191996-10-7
Applications Enantiomer
Formula C22H27ClN4O5
Molecular Weight 462.93
Synonyms (S,S)-HMS-5552; (S,S)-RO-5305552
SMILES
CC(C[C@@H](C(NC1=NN(C=C1)C[C@@H](CO)O)=O)N2CC(OC3=CC=CC=C3Cl)=CC2=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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