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(S)-Thalidomide 4-fluoride

Ligand for E3 Ligase

(S)-Thalidomide 4-fluoride is a selective ligand for the cereblon (CRBN) E3 ligase. This compound is utilized in the synthesis of DeDPP4, making it a valuable tool in research related to protein degradation and the development of targeted therapeutics. Its interaction with the E3 ligase pathway underscores its potential applications in cellular biology and drug discovery initiatives.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	911109-85-8
Applications	Ligand for E3 Ligase
Formula	C₁₃H₉FN₂O₄
Molecular Weight	276.22
SMILES	O=C1N([C@@H](CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.