Fig. 1 · Structure
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(S)-Verapamil hydrochloride
LTC4/calcein Inhibitor
(S)-Verapamil hydrochloride is a potent inhibitor of leukotriene C4 (LTC4) and calcein transport via MRP1. This compound plays a significant role in overcoming drug resistance in tumor cells, potentially eliciting cytotoxic effects. Its applications include cancer research, particularly in studies focused on multidrug resistance mechanisms and the modulation of cellular transport processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 36622-28-3 |
| Applications | LTC4/calcein Inhibitor |
| Formula | C27H39ClN2O4 |
| Molecular Weight | 491.06 |
| Synonyms | (S)-(-)-Verapamil hydrochloride |
| SMILES | COC1=C(OC)C=CC(CCN(C)CCC[C@@](C#N)(C2=CC(OC)=C(OC)C=C2)C(C)C)=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.