Fig. 1 · Structure
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(S)-WAY 100135 dihydrochloride
5-HT Antagonist
(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of the 5-HT 1A receptor, exhibiting an IC50 of 33.9 nM. This compound demonstrates anxiolytic effects in animal models, making it a valuable tool for research in anxiety disorders and related neuropharmacological studies. Its specificity for the 5-HT 1A target enables investigations into serotonin receptor-mediated signaling pathways and their implications in various psychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 149007-54-5 |
| Applications | 5-HT Antagonist |
| Formula | C24H35Cl2N3O2 |
| Molecular Weight | 468.46 |
| SMILES | COC1=C(N2CCN(CC2)C[C@H](C3=CC=CC=C3)C(NC(C)(C)C)=O)C=CC=C1.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.