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S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC50 of 3.24 ?M. S130 suppresses autophagy flux.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.81 mL | 129.04 mL | 258.08 mL |
| 0.5 mM | 5.16 mL | 25.81 mL | 51.62 mL |
| 1 mM | 2.58 mL | 12.9 mL | 25.81 mL |
| 5 mM | 0.52 mL | 2.58 mL | 5.16 mL |
*The above data is based on the productmolecular weight 387.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13376 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1160852-22-1 |
| Formula | C24H25N3O2 |
| M. Wt | 387.47 |
| Purity | >98% |
| Synonyms | S130, S-130 |
| SMILES | O=C1C2=CC=CC=C2C3=C4C1=NC=C(C(NCCCN(CC)CC)=O)C4=CC=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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