Fig. 1 · Structure
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S1647
ASBT/ SOAT Inhibitor
S1647 is a dual inhibitor of the apical sodium-dependent bile acid transporter (ASBT) and sterol O-acyltransferase (SOAT). This compound exhibits significant potential in the study of intrahepatic cholestasis, cholestatic pruritus, and obstipation. Its ability to modulate bile acid transport and cholesterol esterification makes S1647 a valuable reagent for investigating bile acid metabolism and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 259528-99-9 |
| Applications | ASBT/ SOAT Inhibitor |
| Formula | C19H13Cl2N3O5S |
| Molecular Weight | 466.29 |
| SMILES | O=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=CC=C2NS(=O)(C3=CC=CC([N+]([O-])=O)=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.