Trusted by 10,000+ Scientists since 2006

S3I-201 (NSC 74859)


Stat3 Inhibitor

0 Customer Reviews
Catalog No. A10817

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
S3I-201 5mg A10817-5

Regular Price: €38.00

Special Price: €34.20

S3I-201 10mg A10817-10

Regular Price: €66.50

Special Price: €59.85

S3I-201 50mg A10817-50

Regular Price: €166.25

Special Price: €149.63

S3I-201 100mg A10817-100

Regular Price: €313.50

Special Price: €282.15

S3I-201 (NSC 74859) 10mM * 1mL in DMSO A10817-10mM-D

Regular Price: €57.00

Special Price: €51.30

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

S3I-201 (NSC 74859) is a novel inhibitor of Stat3 that inhibits Stat3, Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 ± 33 µM) and Stat3-dependent transcriptional activities.

S3I-201 (NSC 74859)

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
S3I-201 (NSC 74859) Citations (3)
  • Ethan L. Morgan, .et al. STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle, PLoS Pathog, 2018, Apr; 14(4): e1006975 PMID: 29630659
  • Nishimura K, .et al. Effect of erythropoietin production induced by hypoxia on autophagy in HepG2 cells, Biochem Biophys Res Commun, 2018, Jan 1;495(1):1317-1321 PMID: 29191652
  • Soleimani AH, .et al. Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma, Drug Deliv Transl Res, 2017, Aug;7(4):571-581 PMID: 28290050

Chemical Information

Catalog Num A10817
Actions Inhibitor
M. Wt 365.4
Formula C16H15NO7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 501919-59-1
Synonyms S3I201, NSC74859 , NSC-74859

Biological Activity

S3I-201 (NSC 74859) is a novel inhibitor of Stat3 that inhibits Stat3, Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 ± 33 µM) and Stat3-dependent transcriptional activities.
STAT3 (Cell-free assay)
86 μM


Solubility (25°C) * In vitro DMSO 73 mg/mL (199.8 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 5% DMSO, 95% PEG 300 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.37 mL 136.84 mL 273.67mL
0.5 mM 5.47 mL 27.37 mL 54.73 mL
1 mM 2.74 mL 13.68 mL 27.37 mL
5 mM 0.55 mL 2.74 mL 5.47 mL

*The above data is based on the productmolecular weight 365.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Keywords:buy S3I-201 (NSC 74859) | S3I-201 (NSC 74859) Supplier | purchase S3I-201 (NSC 74859) | S3I-201 (NSC 74859) cost | S3I-201 (NSC 74859) manufacturer | order S3I-201 (NSC 74859) | S3I-201 (NSC 74859) distributor | buy 501919-59-1| 501919-59-1 Supplier | purchase 501919-59-1 | 501919-59-1 cost | 501919-59-1 manufacturer | order 501919-59-1 | 501919-59-1 distributor