Fig. 1 · Structure
Documents & Downloads
S961
Insulin Receptor Antagonist
S961 is a high-affinity and selective antagonist of the insulin receptor (IR), exhibiting IC50 values of 0.048 nM for human insulin receptor A (HIR-A), 0.027 nM for human insulin receptor B (HIR-B), and 630 nM for human insulin-like growth factor I receptor (HIGF-IR) in a scintillation proximity assay. This compound is suitable for investigating insulin signaling pathways and exploring the role of insulin resistance in metabolic disorders, making it a valuable tool for researchers studying diabetes and related conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1083433-49-1 |
| Applications | Insulin Receptor Antagonist |
| Formula | C211H295N55O71S2 |
| Molecular Weight | 4802.12 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.