Fig. 1 · Structure

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Salanersen

SMN2 synthesis reducer

Salanersen is an antisense oligonucleotide that specifically targets the survival motor neuron 2 (SMN2) gene, effectively reducing its expression. This compound plays a crucial role in the investigation of spinal muscular atrophy (SMA) by modulating SMN2 levels. Its application is essential for understanding the pathophysiology of SMA and developing potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2701584-16-7
Applications SMN2 synthesis reducer
Formula C234H323O129N80P17S15
Molecular Weight 7328.04
Synonyms BIIB115; ION306

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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