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Salicylate choline

Anti-cancer Agent

Salicylate choline, an orally active derivative of acetylsalicylic acid (Aspirin), functions as an anti-cancer agent through its ability to significantly reduce pro-inflammatory cytokines, including IL-1β, IL-6, TNF-α, and IL-10. This compound enhances the anti-tumor activity of the CRM1 inhibitor Selinexor by inducing S-phase cell cycle arrest and impairing DNA damage repair mechanisms. Research applications include the study of cancer, inflammation, and rheumatic diseases, demonstrating promising anti-tumor efficacy in xenograft models with JeKo-1 cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2016-36-6
Applications	Anti-cancer Agent
Formula	C₁₂H₁₉NO₄
Molecular Weight	241.28
SMILES	O=C(O)C1=CC=CC=C1[O-].C[N+](C)(CCO)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.