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SAM-315

5-Hydroxytryptamine-6 Antagonist

SAM-315 is a potent antagonist of the 5-Hydroxytryptamine-6 receptor, exhibiting a Ki value of 1.1 nM and an IC50 of 4.6 nM. This compound has been shown to significantly enhance the release of acetylcholine and glutamate in the hippocampus, making it valuable for research into neuropharmacology and the modulation of neurotransmitter systems. SAM-315 serves as a useful tool for investigating the role of serotonin receptors in various neurological processes and disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	744218-85-7
Applications	5-Hydroxytryptamine-6 Antagonist
Formula	C₂₁H₂₀N₄O₂S
Molecular Weight	392.47
Synonyms	WAY-255315
SMILES	O=S(C1=NNC2=C1C=C(N3CCNCC3)C=C2)(C4=CC=CC5=C4C=CC=C5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.