Fig. 1 · Structure
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Samatasvir
NS5A Replication Inhibitor
Samatasvir is a potent NS5A replication inhibitor effective against Hepatitis C virus (HCV). It demonstrates selective inhibition of HCV replication, with EC50 values ranging from 2 to 24 pM across various genotypes (1 to 5). This compound is valuable for research applications focused on antiviral drug development and HCV therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1312547-19-5 |
| Applications | NS5A Replication Inhibitor |
| Formula | C47H48N8O6S2 |
| Molecular Weight | 885.06 |
| Synonyms | IDX719; IDX18719 |
| SMILES | O=C(OC)N[C@H](C1=CC=CC=C1)C(N2[C@H](C3=NC=C(C4=CC=C(C5=CSC6=C5SC=C6C7=CC=C8N=C([C@H]9N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC9)NC8=C7)C=C4)N3)CCC2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.