Fig. 1 · Structure
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Sanazole
Radiosensitizer
Sanazole, a hypoxic cell radiosensitizer, primarily enhances radiation-induced DNA strand breaks. In preclinical studies using mouse fibroblast tumors, Sanazole has been shown to increase nuclear condensation and fragmentation, as well as elevate caspase-3 activity. These effects contribute to a significant enhancement of radiation-induced apoptosis, making Sanazole a valuable tool for research in cancer radiotherapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 104958-90-9 |
| Applications | Radiosensitizer |
| Formula | C7H11N5O4 |
| Molecular Weight | 229.19 |
| Synonyms | AK-2123 |
| SMILES | O=C(NCCOC)CN1N=C([N+]([O-])=O)N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.