Fig. 1 · Structure
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Sanggenon G
XIAP Inhibitor
Sanggenon G is a potent inhibitor of the X-linked inhibitor of apoptosis protein (XIAP), targeting the BIR3 domain with a binding affinity of 34.26 μM. This cell-permeable compound enhances caspase activation, facilitating apoptosis in various cell models. Sanggenon G is useful for research applications focused on cell death mechanisms and potential therapeutic development for conditions associated with apoptosis dysregulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 85698-31-3 |
| Applications | XIAP Inhibitor |
| Formula | C40H38O11 |
| Molecular Weight | 694.72 |
| SMILES | O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=CC(O)=C([C@H]4C=C(CC/C=C(C)/C)C[C@@H](C5=CC=C(O)C=C5O)[C@@H]4C(C6=CC=C(O)C=C6O)=O)C(O)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.