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Sapablursen sodium

TMPRSS6 inhibitor

Sapablursen sodium is an antisense oligonucleotide that specifically inhibits TMPRSS6, leading to enhanced expression of hepcidin, a crucial regulator of iron homeostasis. This compound is valuable for investigating its effects on iron regulation and potential applications in the study of blood disorders. Researchers can utilize Sapablursen sodium to explore therapeutic strategies for conditions related to iron dysregulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2273008-00-5
Applications	TMPRSS6 inhibitor
Formula	C₂₉₆H₄₁₆N₈₀Na₂₀O₁₅₅P₂₀S₁₃
Molecular Weight	9071.01
Synonyms	IONIS-TMPRSS6-Lrx sodium; ISIS 702843 sodium

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.