Fig. 1 · Structure

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Sapablursen

TMPRSS6 inhibitor

Sapablursen is an antisense oligonucleotide that specifically inhibits TMPRSS6, leading to enhanced expression of hepcidin, a crucial regulator of iron metabolism. This compound is valuable for research focused on blood disorders, particularly those related to iron regulation and homeostasis. Its ability to modulate hepcidin levels makes it a potential tool for studying various pathophysiological conditions associated with dysregulated iron metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2273007-95-5
Applications TMPRSS6 inhibitor
Formula C296H436N80O155P20S13
Molecular Weight 8631.38
Synonyms IONIS-TMPRSS6-Lrx; ISIS 702843

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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