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Saprisartan

Angiotensin Receptor Antagonist

Saprisartan is a selective angiotensin II type 1 (AT1) receptor antagonist known for its long-acting effects and low receptor dissociation kinetics. It effectively inhibits the binding of angiotensin II, resulting in vasodilation and a decrease in blood pressure. This compound is utilized in research to explore its potential benefits in treating hypertension and related cardiovascular conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	146623-69-0
Applications	Angiotensin Receptor Antagonist
Formula	C₂₅H₂₂BrF₃N₄O₄S
Molecular Weight	611.43
Synonyms	GR 138950
SMILES	O=C(C1=C(C2CC2)N=C(CC)N1CC3=CC=C(OC(C4=CC=CC=C4NS(=O)(C(F)(F)F)=O)=C5Br)C5=C3)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.