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SAR-150640

β3-Adrenoceptor Agonist

SAR-150640 is a selective β3-adrenoceptor agonist that modulates cellular responses by inhibiting matrix metalloproteinase (MMP) activity and production. This compound demonstrates potential therapeutic applications in inflammatory conditions, particularly by reducing the MMP response following lipopolysaccharide (LPS) stimulation and in the context of chorioamnionitis. Its mechanism may provide insights into novel treatments for various inflammatory diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	433212-21-6
Applications	β3-Adrenoceptor Agonist
Formula	C₂₅H₃₅ClN₂O₇S
Molecular Weight	543.07
SMILES	CCOC(C1=CC=C([C@@H]2CC[C@H](CC2)NC[C@H](O)COC3=CC(NS(C)(=O)=O)=C(C=C3)O)C=C1)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.