Fig. 1 · Structure
Documents & Downloads
Sar-Arg-Val-Tyr-Val-His-NH2
Gq-biased Agonis
Sar-Arg-Val-Tyr-Val-His-NH2 is a Gq-biased agonist that demonstrates a tenfold higher molecular efficacy at the AT1R-Gq fusion protein in comparison to the AT1R-βarr2 fusion protein. This compound is essential for studies focused on G protein-coupled receptor signaling pathways and can provide insights into biased signaling mechanisms. Its distinctive mechanism can facilitate research in cardiovascular and neuropharmacological domains, aiding in the investigation of receptor-targeted therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2410957-04-7 |
| Applications | Gq-biased Agonis |
| Formula | C34H54N12O7 |
| Molecular Weight | 742.87 |
| SMILES | CNCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.