Fig. 1 · Structure
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(Sar1)-Angiotensin II
AT1 Agonist
(Sar1)-Angiotensin II is a specific agonist of the angiotensin AT1 receptor. This analogue of Angiotensin II demonstrates a high binding affinity to brain membrane-rich particles, with a Kd value of 2.7 nM. Its biological activity includes the stimulation of protein synthesis and promotion of cell growth in embryonic chick myocytes, making it valuable for research focused on cardiovascular physiology and cellular signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 51833-69-3 |
| Applications | AT1 Agonist |
| Formula | C49H71N13O10 |
| Molecular Weight | 1002.17 |
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.