Fig. 1 · Structure
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(Sar1,Ile4,8)-Angiotensin II
AT1R Agonist
(Sar1,Ile4,8)-Angiotensin II is a selective agonist for the angiotensin II type 1 receptor (AT1R). This compound enhances insulin receptor (IR) signaling and promotes glycogen synthesis in cells. Additionally, (Sar1,Ile4,8)-Angiotensin II increases the insulin-stimulated phosphorylation of key signaling proteins, including Akt and GSK3α/β, making it valuable for research focused on metabolic pathways and insulin-related processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 185461-45-4 |
| Applications | AT1R Agonist |
| Formula | C43H75N13O9 |
| Molecular Weight | 918.14 |
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.