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Sar1,Thr8-Angiotensin II

Angiotensin II Antagonist

[Sar1,Thr8]-Angiotensin II is a selective angiotensin II antagonist that functions by blocking the angiotensin II receptor. This compound demonstrates significant inhibitory activity on angiotensin II signaling pathways, which are crucial in regulating blood pressure and fluid balance. Notably, [Sar1,Thr8]-Angiotensin II has been shown to have minimal effects on cardiac function, indicating potential utility in therapeutic interventions for patients with cardiac conditions. Its application is relevant in cardiovascular research, particularly in studies addressing hypertension and heart disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	53632-49-8
Applications	Angiotensin II Antagonist
Formula	C₄₄H₆₉N₁₃O₁₁
Molecular Weight	956.10
SMILES	C([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC(CNC)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)=O)[C@H](CC)C)=O)(=O)N3[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.