Signaling Pathway
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| Discription | SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays. |
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| Catalog Num | A21094 |
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| Formula | C25H23FN8O2S2 |
| Molecular Weight | 550.63 |
| CAS Number | 1116743-46-4 |
| SMILES | O=C(NCCN1CCOCC1)NC2=NC3=CC=C(SC4=NN=C5C=CC(C6=CC=C(F)C=C6)=NN54)C=C3S2 |
| Synonyms | SAR 125844, SAR-125844 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 11 mg/mL (19.97 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | <1 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.16 mL | 90.81 mL | 181.61 mL |
| 0.5 mM | 3.63 mL | 18.16 mL | 36.32 mL |
| 1 mM | 1.82 mL | 9.08 mL | 18.16 mL |
| 5 mM | 0.36 mL | 1.82 mL | 3.63 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
