SAR125844

Catalog No.: A21094

MET inhibitor

SAR125844

SAR125844 Chemical Structure

CAS NO. 1116743-46-4

SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.

Availability: In stock

Package Price Qty
5 mg
$108.00
10 mg
$186.00
50 mg
$552.00
100 mg
$1,104.00
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Biological Activity

SAR125844 is a potent, highly selective, reversible and ATP-competitive MET receptor tyrosine kinase (RTK) inhibitor, with an IC50 of 4.2 nM. Shows inhibition of MET autophosphorylation in cell-based assays.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.16 mL 90.81 mL 181.61 mL
0.5 mM 3.63 mL 18.16 mL 36.32 mL
1 mM 1.82 mL 9.08 mL 18.16 mL
5 mM 0.36 mL 1.82 mL 3.63 mL

*The above data is based on the productmolecular weight 550.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21094
Actions Inhibitor
M. Wt 550.63
Formula C25H23FN8O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1116743-46-4
Synonyms SAR 125844, SAR-125844
SMILES O=C(NCCN1CCOCC1)NC2=NC3=CC=C(SC4=NN=C5C=CC(C6=CC=C(F)C=C6)=NN54)C=C3S2

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