SAR216471

Catalog No.: A62862
P2Y12 Antagonist
SAR216471 is a selective P2Y12 receptor antagonist that reversibly inhibits the binding of 2MeSADP to P2Y12 receptors, demonstrating an IC50 of 17 nM in vitro. This compound effectively inhibits platelet aggregation and displays anti-thrombotic activity in rat models. SAR216471 is pertinent for investigations into thrombosis and related cardiovascular research applications.
Grouped product items
Size Price Stock Qty
5mg
$350.00
In stock
10mg
$650.00
In stock
50mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSAR216471 is a selective P2Y12 receptor antagonist that reversibly inhibits the binding of 2MeSADP to P2Y12 receptors, demonstrating an IC50 of 17 nM in vitro. This compound effectively inhibits platelet aggregation and displays anti-thrombotic activity in rat models. SAR216471 is pertinent for investigations into thrombosis and related cardiovascular research applications.
Product Information
Catalog NumA62862
FormulaC28H31ClN8O3
Molecular Weight563.05
CAS Number1279867-21-8
SMILESO=C(CCC)C1=C(C)N(C2=NN=C(NC(C3=CN(CC(N4CCN(C)CC4)=O)C5=C3C=C(Cl)C=C5)=O)C=C2)N=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2