Fig. 1 · Structure

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Saralasin acetate hydrate

Angiotensin II Receptor Antagonist

Saralasin acetate hydrate is a competitive angiotensin II receptor antagonist that exhibits a Ki value of 0.32 nM for a significant proportion of binding sites, alongside partial agonist activity. This octapeptide analog of angiotensin II is valuable in the study of renovascular and renin-dependent hypertension. Its dual activity makes it a useful tool for investigating the physiological effects of angiotensin II and its role in hypertension-related research.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 39698-78-7
Applications Angiotensin II Receptor Antagonist
Formula C44H71N13O13
Molecular Weight 990.11
Synonyms [Sar1,Ala8] Angiotensin II acetate hydrate
SMILES
CC(C)[C@@H](C(N[C@@H](Cc1cnc[nH]1)C(N(CCC1)[C@@H]1C(N[C@@H](C)C(O)=O)=O)=O)=O)NC([C@H](Cc(cc1)ccc1O)NC([C@H](C(C)C)NC([C@H](CCCN=C(N)N)NC(CNC)=O)=O)=O)=O.CC(O)=O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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