Fig. 1 · Structure
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Sarcophine
GlyR Inhibitor
Sarcophine is a potent inhibitor of the glycine receptor (GlyR), exhibiting an IC50 value of 3.9 μM. This natural product is derived from the Red Sea soft coral Sarcophyton glaucum. Sarcophine serves as a valuable tool for research into glycine receptor-mediated signaling pathways and their roles in neurological conditions. Its inhibitory action provides insights into potential therapeutic approaches for disorders involving glycine receptor dysfunction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 55038-27-2 |
| Applications | GlyR Inhibitor |
| Formula | C20H28O3 |
| Molecular Weight | 316.43 |
| Synonyms | (+)-Sarcophine |
| SMILES | O=C1C(C)=C2[C@](O1)([H])/C=C(C)/CC[C@H]3[C@](O3)(C)CC/C=C(C)/CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.