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$0.00 Biological Activity
Saridegib is a potent and specific inhibitor of Smoothened (Smo), a key signaling transmembrane protein in the Hedgehog (Hh) pathway.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.81 mL | 99.06 mL | 198.11 mL |
| 0.5 mM | 3.96 mL | 19.81 mL | 39.62 mL |
| 1 mM | 1.98 mL | 9.91 mL | 19.81 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
*The above data is based on the productmolecular weight 504.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12966 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 504.77 |
| Formula | C29H48N2O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1037210-93-7 |
| Synonyms | IPI-926; Patidegib, IPI926, IPI 926 |
| SMILES | CC1=C(C[[email protected]@]2([H])[[email protected]@]3([H])CC[[email protected]@]4([H])[[email protected]]2(C)CC[[email protected]@H](NS(C)(=O)=O)C4)[[email protected]@]3([H])CC[[email protected]@]([[email protected]@H]5C)(C1)O[[email protected]@]6([H])[[email protected]@]5([H])NC[[email protected]@H](C)C6 |
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