Sarizotan dihydrochloride is a potent agonist of the serotonin 5-HT1A receptor and dopamine receptors. It demonstrates strong activity with IC50 values of 6.5 nM for rat 5-HT1A, 0.1 nM for human 5-HT1A, 15.1 nM for rat D2, 17 nM for human D2, 6.8 nM for human D3, and 2.4 nM for human D4.2. Sarizotan dihydrochloride is utilized in research to explore neuropharmacology, behavior, and potential therapeutic effects on psychiatric disorders.
Sarizotan dihydrochloride is a potent agonist of the serotonin 5-HT1A receptor and dopamine receptors. It demonstrates strong activity with IC50 values of 6.5 nM for rat 5-HT1A, 0.1 nM for human 5-HT1A, 15.1 nM for rat D2, 17 nM for human D2, 6.8 nM for human D3, and 2.4 nM for human D4.2. Sarizotan dihydrochloride is utilized in research to explore neuropharmacology, behavior, and potential therapeutic effects on psychiatric disorders.
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