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SARM1-IN-6

SARM1 Inhibitor

SARM1-IN-6 is a potent orthosteric inhibitor of SARM1, demonstrating an IC50 value of 0.069 μM against NAM. This compound is brain-permeable, making it particularly valuable for neuroscientific research. SARM1-IN-6 is applicable in studies related to neuronal injury and degeneration, contributing to the understanding of neuroinflammatory processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3080315-51-8
Applications	SARM1 Inhibitor
Formula	C₂₀H₁₉F₂N₃O
Molecular Weight	355.38
SMILES	O=C1N(CC[C@H](C2=CN=C(F)C(F)=C2)C1)C34CC(C4)(C5=CC=NC=C5)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.