Fig. 1 · Structure
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SARS-CoV-2 3CLpro-IN-6
CoV-2 3CL Protease Covalent Inhibitor
SARS-CoV-2 3CLpro-IN-6 is a reversible covalent inhibitor specifically targeting the 3CL protease of SARS-CoV-2. Demonstrating potent inhibitory activity with an IC50 of 4.9 μM, this compound is valuable for studying the mechanisms underlying coronavirus disease 2019 (COVID-19). Its efficacy makes it a crucial tool in research aimed at understanding and developing treatments for SARS-CoV-2 infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 302821-53-0 |
| Applications | CoV-2 3CL Protease Covalent Inhibitor |
| Formula | C22H15NO7 |
| Molecular Weight | 405.36 |
| SMILES | COC(C(/C(C(C1=CC=CC=C1)=O)=C\C2=CC=C(O2)C3=C(C=CC=C3)[N+]([O-])=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.