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Sauristolactam

Name: Sauristolactam
Brand: Adooq Bioscience
SKU: A13648
Availability: InStock

Cat. No. A13648 CAS 128533-02-8

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells.

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Biological Activity

Cellular Effect

Cell Line	Activity	Value	Description	Reference
HCT-15	GI50	4.1 μM	Antiproliferative activity against human HCT15 cells by SRB assay	[PMID: 19394218]
HCT-15	GI50	4.38 μM	Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay	[PMID: 19394218]
MES-SA	GI50	23.75 μM	Antiproliferative activity against human MESSA cells by SRB assay	[PMID: 19394218]
MES-SA/Dx5	GI50	23.11 μM	Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay	[PMID: 19394218]

Specifications

Manufacturer	Adooq Bioscience
CAS Number	128533-02-8
Formula	C₁₇H₁₃NO₃
Molecular Weight	279.29
Synonyms	Saurolactam
SMILES	O=C1N(C2=C3C1=CC(O)=C(C3=C4C(C=CC=C4)=C2)OC)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.